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Jessica Natali is a white-collar criminal defense attorney and former Assistant U.S. Attorney for the Eastern District of Pennsylvania. She has deep experience both prosecuting and defending a wide range of criminal and civil cases, particularly health care fraud and opioid cases involving doctors, pharmacists, and health care entities. Jessica also specializes in federal and state grand jury investigations. Jessica has handled matters involving health care fraud, Medicare/Medicaid fraud, financial services fraud, public corruption, election and campaign fraud, mail fraud, wire fraud, mortgage fraud, tax fraud, securities fraud, national security cases involving IEEPA, immigration fraud, government contracting fraud, bankruptcy fraud, and money laundering, as well as assorted violent crime matters. She represents corporations and individuals in federal and state criminal cases, complex white-collar defense matters, internal investigations, as well as civil litigation and investigations involving the defense of qui tam/False Claims Act complaints and products liability cases. Jessica also assists clients to build and implement compliance policies and procedures consistent with the elements of an effective compliance program under DOJ guidelines.

Jessica currently represents clients from a broad array of industries in criminal and civil matters including large medical device manufacturers, doctor practices and individuals from pharmaceutical companies in investigations involving health care fraud, violations of HIPAA, Medicaid/Medicare billing fraud, violations of the Stark Law, the Anti-Kickback Statute, the False Claims Act and complex civil litigation. Jessica also represents or has represented high level executives of banking institutions and public officials investigated for a variety of different alleged offenses including public corruption, campaign finance violations, fraud, theft, and sexual misconduct allegations.

Jessica has advised and worked closely with a variety of federal and local law enforcement agencies, including: The Federal Bureau of Investigation, The Drug Enforcement Administration, The United States Department of Health and Human Services, The Internal Revenue Service, Office of the Comptroller of the Currency, Homeland Security Investigations, The Bureau of Alcohol, Tobacco, Firearms and Explosives, The United States Postal Service, offices of attorneys general, police departments, and district attorney’s offices.


  • White collar criminal defense
  • Government investigations
  • Internal investigations and compliance
  • False Claims Act qui tam cases
  • Health care fraud
  • Tax fraud
  • Business fraud



  • Representation of key employees of pharmaceutical company in a False Claims Act investigation conducted by DOJ.
  • Representation of large medical device company in a False Claims Act investigation conducted by DOJ.
  • Representation of health care entity in both a False Claims Act investigation and a parallel grand jury investigation conducted by the Pennsylvania Office of the Attorney General and DOJ.
  • Representation of national medical laboratory in connection with a False Claims Act investigation and a parallel criminal investigation conducted by DOJ.
  • Representation of key individual in a criminal and civil opioid investigation involving large pharmacy chain conducted by DOJ and state pharmacy board.
  • Internal investigation related to employee misconduct at skilled nursing facility.
  • Investigation and defense of the CEO of a Pennsylvania bank in a DOJ and OCC regulatory matter focused on former senior trust officer who mismanaged funds causing bank to repay customers $1.2 million.
  • Investigation and defense of Pennsylvania State Representative in a grand jury matter and prosecution by the Pennsylvania Office of the Attorney General.
  • Representation of large medical device manufacturer in multi-district litigation including overseeing Pennsylvania team in over 100 remanded federal cases.
  • Oversight of all complex third-party subpoenas for large international corporation.
  • U.S. v. Dr. Kermit Gosnell, et al.: Dr. Gosnell, along with other health care professionals, ran an opioid “pill mill” and was convicted of conspiracy to distribute over a million tablets of Oxycodone and Xanax and maintaining a place for the illegal distribution of controlled substances. The case involved 17 defendants. Dr. Gosnell was sentenced to 30 years’ imprisonment.°
  • In U.S. v. Kirk Kirby et al., investigated and prosecuted an $8 million Ponzi-type investment/mortgage fraud scheme involving Invictus Financial Group (“IFG”). This prosecution effectively closed down IFG and lead to convictions of multiple individuals including an accountant, a loan officer at a brokerage company, and the owner of IFG. This case had national implications and spanned across multiple states as the defendants placed fraudulent documents into the public record, destroyed unsuspecting dupes’ credit histories, artificially inflated property values, and ultimately contributed to the collapse of the housing market and our nation’s financial crisis.°
  • In U.S. v. Vontia Jones et al. and U.S v. Sharon Price et al., investigated and prosecuted a multimillion-dollar complex tax fraud and identity theft scheme involving more than 1,000 fraudulent returns leading to the guilty pleas and conviction of multiple individuals. Jones, Price and their co-conspirators defrauded hundreds of individuals in the Philadelphia region by posing as tax preparers, operating fraudulent tax service businesses and funneling the illegal proceeds through business accounts and personal accounts at multiple victim banks.°
  • In U.S. v. Joseph DiCastelnuevo et al., investigated and prosecuted the owner and operator of an automobile repair shop who, along with his brother, defrauded insurance companies by submitting fraudulent claims based on damages they intentionally made to cars. The scheme involved more than $1 million in false claims submitted to at least 18 victim insurance companies. This prosecution lead to guilty pleas and convictions of all defendants.°
  • In U.S. v. Lynward Brown et al., Brown, investigated and prosecuted a Philadelphia Federal Credit Union (PFCU) employee, who conspired with other individuals to commit bank fraud and identity theft and funnel over a hundred thousand dollars from the victims’ PFCU bank accounts. This prosecution lead to guilty pleas and convictions of all defendants.°
  • In U.S. v. William Caton, investigated and prosecuted an individual for income tax evasion and failing to report over 2.4 million dollars. Caton set up shell companies and defrauded various companies and individuals. This prosecution led to a guilty plea and conviction.°
  • In U.S. v. Mariani et al., investigated and prosecuted a husband and wife who ran a business filed fraudulent tax returns and hid gross receipts totaling nearly half a million dollars. This prosecution led to guilty pleas and convictions of all defendants.°
  • U.S. v. Jon Lackner: Dr. Lackner used interstate communications to attempt to induce a minor to engage in illegal sexual activity, traveled with intent to engage in illicit sexual conduct with a minor, and attempted the transfer of obscene material to a minor. After trial, he was sentenced to 15 years’ imprisonment.°
  • U.S. v. Blair Thomas: Mr. Thomas committed two armed bank robberies and two armed robberies of post offices. After trial, he was sentenced to 32 years’ imprisonment.°
  • Led the representation of nine Philadelphia-area community organizations, who appeared as amici curiae, and filed a brief in support of Safehouse in the action United States v. Safehouse, in the U. S. District Court for the Eastern District of PA and also in the U.S. Court of Appeals for the Third Circuit.
  • Defended various indigent criminal defendants in pro bono cases as a member of the Criminal Justice Act Appointment Panel for the U.S. District Court for the District of Pennsylvania (2004-2007) and the U.S. Court of Appeals for the Third Circuit (2002-2007).° 

°The above representations were handled by Ms. Natali prior to her joining Greenberg Traurig, LLP.

  • Assistant U.S. Attorney, U.S. Attorney’s Office for the Eastern District of Pennsylvania, 2007-2018
  • Summer Clerk, Hon. Stanley S. Brotman, U.S. District Court for the District of New Jersey, 1998

Recognition & Leadership

  • Team Member, a Law360 “Product Liability Practice Group of the Year,” 2021
  • Listed, Chambers USA Guide, Litigation: White-Collar Crime & Government Investigations, 2021
  • Listed, The Legal 500 United States, Dispute Resolution - Corporate Investigations and White-Collar Criminal Defense, 2019
  • Recognized, United States Postal Inspection Service, “Outstanding Prosecutorial Work,” 2015
  • Recipient, Pennsylvania Narcotics Officers’ Association, “Outstanding Prosecutor Award," 2014 
  • Recipient, U.S. Department of Health and Human Services, “Integrity Award,” 2014
  • Recipient, Drug Enforcement Administration, “Outstanding Contribution Award,” 2014 
  • Recipient, Federal Bureau of Investigation, “Demonstrated Excellence Award,” 2013 
  • Named, Leadership Philadelphia, “Philadelphia Connector,” 2008
  • Listed, Super Lawyers magazine, Pennsylvania Super Lawyers, “Rising Stars,” 2006-2008
  • Adjunct Professor, Temple University, Beasley School of Law, Sentencing Advocacy Course, 2020-Present
  • University of Pennsylvania Law School, American Inn of Court, Member, 2019-Present
  • Women’s White Collar Defense Association (WWCDA)
    • Member 2019-Present
    • Events Committee Co-Chair, 2019-2020
  • Pennsylvania Association of Criminal Defense Lawyers (PACDL 2004-2007; 2019-Present
    • Course Planner, PACDL White Collar Seminar, 2019-2020
    • Board Member, 2004-2007
    • Co-Chair, Young Lawyers Division, 2004-2006
    • Co-Chair, CLE Committee “For the Experienced” Seminar, 2003-2006
  • Federal Criminal Law Committee for the Eastern District of Pennsylvania, 2019-Present
    • Chair, 2022
    • Vice Chair, 2021
    • Officer and Treasurer, 2019-2020
  • GT Women’s Initiative Liaison, Philadelphia Office, 2019-Present
  • GT Communications Forum Leadership Committee, Philadelphia Office, 2020-Present
  • Former Member, National Association of Assistant U.S. Attorneys, 2007-2018
    • Board Member, 2015-2017
    • Delegate for the U.S. Attorney’s Office for the Eastern District of Pennsylvania, 2015-2017
  • Member, American Bar Association, 2004-2010
    • Co-Founder and Co-Chair, Philadelphia Chapter of the Criminal Justice Section’s White Collar Crime Committee Young Lawyers Division, 2004-2010
    • Member, National Steering Committee of the Criminal Justice Section’s White Collar Crime Committee Young Lawyers Division, 2004-2007
    • Co-Chair, Membership for Criminal Committee of Litigation Section, 2003-2007
  • Professional Women’s Roundtable Board Member and Co-Chair Membership/Marketing Committee, 2003-2007
  • Pennsylvania Animal Welfare Society (PAWS), Volunteer and Donor, 2015-Present
  • Rydal Elementary Parent Teacher Organization, Volunteer, 2008-2016
  • People’s Emergency Center, Volunteer, 1998-2009
  • Philadelphia Reads, Volunteer, 2000-2001 and 2007-2008
  • United Way, Member 2001-2007
    • Member, Women’s Initiative Steering Committee, 2002-2007
    • Member, Young Leader’s Program, 2001-2007
  • Women’s Way Advocacy Education Steering Committee, Member, 2004-2007


  • J.D., summa cum laude, Temple University Beasley School of Law
    • Articles/Symposium Editor, Temple Law Review
  • B.S., Drexel University
  • U.S. Court of Appeals for the Third Circuit, 2000-2001
  • Pennsylvania
  • U.S. District Court for the Eastern District of Pennsylvania
  • U.S. Court of Appeals for the Third Circuit