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Natalie Wayne represents corporations and individuals in complex federal white collar and regulatory defense and internal investigations, as well as in complex litigation in federal and state courts.

Natalie’s white collar and investigations practice spans a wide range of sectors and subject areas. She advises clients in matters involving the False Claims Act (FCA), fraud, and consumer protection.

Natalie’s civil litigation practice involves matters related to business disputes, FCA, qui tam, mass torts, and antitrust issues. She has experience advising clients at all phases of litigation, including initial fact investigation, written discovery, defending and taking depositions, briefing and arguing dispositive motions, and preparing for trial. In particular, Natalie has deep experience in eDiscovery, including designing and implementing procedures for preserving and producing electronically stored information. Her recent experience includes managing large-scale civil monopolization and conspiracy antitrust lawsuits across various products and industries, including financial services and eTechnology, and a Fortune 100 company’s nationwide defense of lawsuits related to alleged per- and polyfluoroalkyl substances (PFAS) contamination.


  • Products liability and mass torts
  • Antitrust
  • Environmental litigation
  • eDiscovery
  • FCA
  • PFAS



  • Extern, Hon. Virginia M. Kendall, U.S. District Court for the Northern District of Illinois, 2011
  • Undergraduate Intern, U.S. Senator Richard J. Durbin, 2005

Recognition & Leadership

  • Listed, Emerging Lawyer, Leading Lawyers Network, 2023


  • J.D., magna cum laude, Loyola University Chicago School of Law, 2013
    • Tax Law Certificate
    • Managing Editor, Loyola University Chicago Law Journal
  • B.S., cum laude, Georgetown University, Edmund A. Walsh School of Foreign Service, 2008
  • Illinois